Michal Sýkora debuted as a novelist in 2012 with A Case for an Exorcist / Případ pro exorcistu, the first of his highly successful sequence featuring Commissioner Výrová, which Host is now in 2021 releasing in a new edition. It is followed in the series by Blue Shadows / Modré stíny (2013), It’s Not Over Yet / Ještě není konec (2016), Five Dead Dogs / Pět mrtvých psů (2018) and Worst Fears/ Nejhorší obavy (2020). The TV mini-series sequence Detektivové od Nejsvětější Trojice [= Detectives of the Holy Trinity] (2015—2019) is based on Sýkora’s Výrová novels; popular with viewers and critics alike, it has also been shown abroad.
With Petr Jarchovský, Michal Sýkora has written screenplays for the Czech Television mini-series Živé terče [= Live Targets] (2019) and the forthcoming Pozadí událostí [= Background to Events]. Michal Sýkora is the author of monographs on Vladimir Nabokov (2002, 2004) and Philip Roth (2019).
Michal Sýkora's books have been published in four languages: Arabic, Bulgarian, Macedonian and Polish.
The author's work is presented in the anthology Prague Noir (Akashic 2017, USA).